Various imaging methods allow evaluation in vivo

V ulnerable plaques are defined as nonobstructive atherosclerotic lesions that are prone to rupture, causing arterial thrombosis and leading to, for example, acute coronary syndromes (ACS) and stroke.1,2 A deep understanding of the pathophysiology of vulnerable plaque could play a key role in optimizing the prevention and treatment of arterial thrombosis, potentially reducing its morbidity and mortality. We discuss the recent advances in noninvasive and intravascular imaging that have significantly improved the ability to evaluate vulnerable plaque in vivo.3,4